
Awakening the Skin's Regenerative Potential
The SAISEICO Regenerative Skin EXCELLENE⁺ series of products is recognized as a legendary craftsmanship in Japanese skincare by its dedication to quality and attention to detail. Each product is manufactured in a GMP-certified pharmaceutical factory, ensuring a safe and reliable skincare experience for you.
SAISEICO's mission is to unleash and perfect the skin's innate regenerative potential, so that your skin glows with natural beauty.
Ace Ingredients
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"DUAL" EXOSOME
- Utilization of high quality mesenchymal stem cells
- Unique 3D culture technology
- Produced by GMP certified pharmaceutical company in Japan
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NAD⁺
- Promote DNA repair and protect cell health
- Delay cellular aging
- Antioxidant and Inflammation Regulation
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FULLERENE
- 50 Times The Potency Of Vitamin C
- Free Radical Scavenger
- Protects against UV rays
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GROWTH FACTORS
- Promote skin cell metabolism
- Accelerates healing after surgery
- Prevent pigmentation, anti-aging
Collapsible content

Umbilical cord blood exosomes
1. Exosomes derived from umbilical cord mesenchymal stem cells (UC-MSCs) have been shown to improve immune modulation, stimulate angiogenesis, promote keratinocyte proliferation, and mediate extracellular matrix remodeling, thereby promoting wound healing and skin regeneration
2. Anti-aging, reducing wrinkles, improving skin texture and hydration, and enhancing skin elasticity
Adipocyte exosomes
1. Exosomes released by adipose-derived stem cells (ADSCs) have regenerative and anti-inflammatory effects on the skin, helping to improve its appearance and texture
2. Enhance cell proliferation, mediate tissue regeneration by regulating inflammatory responses, promoting cell proliferation, and inducing angiogenesis
Reverse TimeRevive Youthful Brilliance
NAD⁺

Definition of NAD⁺
NAD⁺ is a coenzyme found in all living cells, essential for various cellular processes such as DNA repair, metabolism, and cell signaling. As we age, NAD⁺ levels naturally decline, leading to decreased cellular function and an increase in age-related diseases.
10 Major Benefits
- Enhance Cellular Energy
- Improve DNA Repair
- Reduce Wrinkles
- Improve Skin Hydration
- Combat Oxidative Stress
- Promote Collagen Production
- Support Skin Regeration
- Reduce Inflammation
- Enhance Skin Elasticity
- Prevent Sun Damage
Effective Against Free Radical DamagePrevention and Mitigation of Aging
FULLERENE

250 Times The Potency Of Vitamin C
Fullerenes, recognized by a Nobel Prize, are super powerful antioxidant molecules. Their antioxidant power is 250 times that of Vitamin C, making them one of the strongest antioxidant components currently available
4 Major Effects
- Improve the aging issues of the skin base and maintain skin elasticity
- Achieve whitening effects by indirectly inhibiting melanin production through free radical scavenging
- Deeply penetrate the skin for more complete nourishment
- Fill in fine lines and wrinkles for more even and smooth skin texture. Over 1500 medical aesthetic clinics in Japan use fullerene products as post-surgery care
Endow aging cells with brand new vitality
GROWTH FACTORS

Growth Factor Blend
The guardian of growth factors. Artificial enhancement is done by adding superoxide dismutase (SOD) to growth factors. Using natural growth factors together can deliver numerous growth factors to deeper layers while protecting the more vulnerable growth factors from various substances
The Fountain Of Life ThatNurtures New Cells
Growth factors are proteins or hormone-like substances secreted by cells, which promote cell growth, differentiation, and survival. They play a crucial role in various physiological processes in the human body
6 Major Effects
- Anti-aging and promoting cell proliferation
- Fading dark spots
- Supporting cell differentiation
- Accelerating wound healing
- Stimulating cell metabolism
- Promoting skin repair
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Promotes cell proliferation
Reduces hyperpigmentation
Supports cell differentiation -
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Accelerates wound healing
Stimulates cell metabolism
Promotes skin repair
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Nahlsgen
Elastic Protein +150%
Increases Skin ElasticityFirmness and ShineHPS47 +150%
Provides vitality for the skinHas hydrated skinCollagen +300%
Activate skin cellsIncrease collagen -
Oligopeptide-20
Elastin +140%
Lock in skin moisture
Maintain hydrated
and radiant skin
Fibronectin +430%
Stimulate cells to secrete functional proteins
Help repair damaged cells
Collagen +140%
Help skin retain moisture
Tighten skin pores
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Oligopeptide-24
Hyaluronic Acid +300%
Smooth fine lines
Reveal a youthful skin
Elastic Protein +130%
Promote Cell Proliferation
Maintain Skin Elasticity
Help ingredients to reach deeper layers more effectively Awaken dormant cells and enhance their regenerative potential
Nano DeliverySystem (NDS)

Sustained release of active ingredients
NDS provides controlled and sustained release of active ingredients by encapsulating them within nanoparticles.
Enhancing the stability and bioavailability of the ingredients.
Direct penetration through skin barrier
NDS is tailored to specific formulations and active ingredients by adjusting particle size, surface charge, nanoparticle fraction, release profile and performance to meet Japanese quality standards.
Enhanced ingredient stability
Encapsulating active ingredients in NDS prevents degradation and increases their stability. It can extend the shelf life and maintain the effectiveness of the ingredients for a long time.
Before & After

The Beauty of a Bare Face
After 4 treatments - Significant improvement in skin condition
+159% Brighter
+125% Firmer
+250% More Hydrated
+194% Smooth