The SAISEICO Regenerative Skin EXCELLENE⁺ series of products is recognized as a legendary craftsmanship in Japanese skincare by its dedication to quality and attention to detail. Each product is manufactured in a GMP-certified pharmaceutical factory, ensuring a safe and reliable skincare experience for you.
SAISEICO's mission is to unleash and perfect the skin's innate regenerative potential, so that your skin glows with natural beauty.


Japan GMP Certificate

Ace Ingredients

"DUAL"EXOSOME
· Utilization of high quality mesenchymal stem cells
· Unique 3D culture technology
· Produced by GMP certified pharmaceutical
company in Japan

NAD⁺
· Promote DNA repair
and protect cell health
· Delay cellular aging
· Antioxidant and
Inflammation Regulation

FULLERENE
· 50 Times The Potency Of Vitamin C
· Free Radical Scavenger
· Protects against UV rays

GROWTH FACTORS
· Promote skin cell metabolism
· Accelerates healing after surgery
· Prevent pigmentation, anti-aging
“DUAL”EXOSOME
New Anti-Ageing Technology Exploration
1. Exosomes derived from umbilical cord mesenchymal stem cells (UC-MSCs) have been shown to improve immune modulation, stimulate angiogenesis, promote keratinocyte proliferation, and mediate extracellular matrix remodeling, thereby promoting wound healing and skin regeneration
2. Anti-aging, reducing wrinkles, improving skin texture and hydration, and enhancing skin elasticity
1. Exosomes released by adipose-derived stem cells (ADSCs) have regenerative and anti-inflammatory effects on the skin, helping to improve its appearance and texture
2. Enhance cell proliferation, mediate tissue regeneration by regulating inflammatory responses, promoting cell proliferation, and inducing angiogenesis
NAD⁺
Reverse Time
Revive Youthful Brilliance
1. Enhance Cellular Energy
2. Improve DNA Repair
3. Reduce Wrinkles
4. Improve Skin Hydration
5. Combat Oxidative Stress
6. Promote Collagen Production
7. Support Skin Regeration
8. Reduce Inflammation
9. Enhance Skin Elasticity
10. Prevent Sun Damage
FULLERENE
Effective Against Free Radical Damage
Prevention and Mitigation of Aging
Fullerenes, recognized by a Nobel Prize, are super powerful antioxidant molecules. Their antioxidant power is 250 times that of Vitamin C, making them one of the strongest antioxidant components currently available
1. Improve the aging issues of the skin base and maintain skin elasticity
2. Achieve whitening effects by indirectly inhibiting melanin production through free radical scavenging
3. Deeply penetrate the skin for more complete nourishment
4. Fill in fine lines and wrinkles for more even and smooth skin texture. Over 1500 medical aesthetic clinics in Japan use fullerene products as post-surgery care
GROWTH
FACTORS
Endow aging cells with
brand new vitality
The Fountain Of Life That
Nurtures New Cells
Growth factors are proteins or hormone-like substances secreted by cells, which promote cell growth, differentiation, and survival. They play a crucial role in various physiological processes in the human body
1. Anti-aging and promoting cell proliferation
2. Fading dark spots
3. Supporting cell differentiation
4. Accelerating wound healing
5. Stimulating cell metabolism
6. Promoting skin repair

Promoting cell proliferation




Accelerating wound healing



Elastic Protein +150%
Increases Skin Elasticity
Firmness and Shine
HPS47 +150%
Provides vitality for the skin
Has hydrated skin
Collagen +300%
Activate skin cells
Increase collagen

Elastin +140%
Lock in skin moisture
Maintain hydrated
and radiant skin
Fibronectin +430%
Stimulate cells to secrete functional proteins
Help repair damaged cells
Collagen +140%
Help skin retain moisture
Tighten skin pores

Hyaluronic Acid +300%
Smooth fine lines
Reveal a youthful skin
Elastic Protein +130%
Promote Cell Proliferation
Maintain Skin Elasticity
Nano Delivery
System (NDS)
Help ingredients to reach deeper layers more effectively Awaken dormant cells and enhance their regenerative potential
NDS provides controlled and sustained release of active ingredients by encapsulating them within nanoparticles.
Enhancing the stability and bioavailability of the ingredients.
NDS is tailored to specific formulations and active ingredients by adjusting particle size, surface charge, nanoparticle fraction, release profile and performance to meet Japanese quality standards.
Authentic Japan
Clinical Evidence
The Beauty
of a Bare Face
After 4 treatments
Significant improvement in skin condition
+159%
brighter
+125%
Firmer
+250%
more hydrated
+194%
smoother
Revitalize Skin with
Renewed Life Energy
